関連する実験動画

Updated: Apr 27, 2026

Site Directed Spin Labeling and EPR Spectroscopic Studies of Pentameric Ligand-Gated Ion Channels
11:19

Site Directed Spin Labeling and EPR Spectroscopic Studies of Pentameric Ligand-Gated Ion Channels

Published on: July 4, 2016

9.9K

トリアリルメチル基のスピンラベルとパルス二極性EPRスペクトロスコーピーを用いて核酸で生理気温距離測定

Georgiy Yu Shevelev1, Olesya A Krumkacheva, Alexander A Lomzov

  • 1Institute of Chemical Biology and Fundamental Medicine, §International Tomography Center, and #N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of the Sciences (SB RAS) , Novosibirsk 630090, Russia.

Journal of the American Chemical Society
|June 26, 2014
PubMed
まとめ

研究者は,電子パラマグネティック共振 (EPR) を使用して,体温でDNAのナノメートルスケールの距離を測定しました. この画期的な発見により,自然で生理的な条件下で核酸の構造を研究することが可能になった.

さらに関連する動画

Use of Electron Paramagnetic Resonance in Biological Samples at Ambient Temperature and 77 K06:45

Use of Electron Paramagnetic Resonance in Biological Samples at Ambient Temperature and 77 K

Published on: January 11, 2019

9.1K
High-Speed Magnetic Tweezers for Nanomechanical Measurements on Force-Sensitive Elements08:50

High-Speed Magnetic Tweezers for Nanomechanical Measurements on Force-Sensitive Elements

Published on: May 12, 2023

3.1K

関連する概念動画

Atomic Nuclei: Nuclear Spin State Population Distribution01:14

Atomic Nuclei: Nuclear Spin State Population Distribution

Near absolute zero temperatures, in the presence of a magnetic field, the majority of nuclei prefer the lower energy spin-up state to the higher energy spin-down state. As temperatures increase, the energy from thermal collisions distributes the spins more equally between the two states. The Boltzmann distribution equation gives the ratio of the number of spins predicted in the spin −½ (N−) and spin +½ (N+) states.
1.7K
¹H NMR of Conformationally Flexible Molecules: Variable-Temperature NMR01:15

¹H NMR of Conformationally Flexible Molecules: Variable-Temperature NMR

The axial and equatorial protons in cyclohexane can be distinguished by performing a variable-temperature NMR experiment. In this process, except for one proton, the remaining eleven protons are replaced by deuterium. The deuterium substitution avoids the possible peak splitting caused by the spin-spin coupling between the adjacent protons. The remaining proton flips between the axial and equatorial positions.
1.3K
Applications Of NMR In Biology01:25

Applications Of NMR In Biology

Nuclear magnetic resonance (NMR) spectroscopy is a very valuable analytical technique for researchers. It has been used for more than 50 years as an analytical tool. F. Bloch and E. Purcell formulated NMR in 1946 and won the 1952 Nobel Prize in Physics  for their work. Biological macromolecules such as proteins, nucleic acids, lipids, and organic molecules including pharmaceutical compounds, can be studied using this versatile tool that exploits the magnetic properties of certain nuclei.
3.3K