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Methods to Identify the NMR Resonances of the 13C-Dimethyl N-terminal Amine on Reductively Methylated Proteins
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O-アミノフェノールによるタンパク質のN端末改変

Allie C Obermeyer1, John B Jarman, Matthew B Francis

  • 1Department of Chemistry, University of California, Berkeley , Berkeley, California 94720, United States.

Journal of the American Chemical Society
|June 26, 2014
PubMed
まとめ

新しい酸化戦略により,容易に入手可能な試薬を使用して,効率的なN端タンパク質改変が可能になります. この方法は,迅速でサイト選択的な機能化を提供し,貴重なバイオコンジュガートを生み出します.

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