アルコール摂取,特定のアルコール飲料,腹部大動脈動脈瘤
Otto Stackelberg1, Martin Björck2, Susanna C Larsson2
1From the Unit of Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden (O.S., S.C.L., N.O., A.W.); and the Department of Surgical Sciences, Section of Vascular Surgery, Uppsala University, Uppsala, Sweden (M.B.). otto.stackelberg@ki.se.
Circulation
|June 27, 2014
まとめ
ビールやワインなどの適度なアルコール摂取は,腹動脈動脈瘤 (AAA) のリスクを低下させる可能性があります. より高いアルコール摂取量とAAA開発に関するさらなる研究が必要である.
科学分野:
- 心血管伝染病学 心血管伝染病学
- 血管疾患の研究研究
- アルコール消費量 研究 アルコール消費量 研究
背景:
- アルコールの腹動脈動脈瘤 (AAA) 発症への影響に関する研究は限られている.
- アルコール摂取とAAAリスクとの関係を調査することは極めて重要です.
研究 の 目的:
- 総アルコール摂取量と特定の飲料の間で,AAAを発症するリスクとの関連性を調べる.
- アルコールとAAAの関連性を理解するために,スウェーデンの大規模なコホートからのデータを分析する.
主な方法:
- スウェーデンの男性コホートとスウェーデンのマンモグラフィーコホートのデータに基づいてコックス比例リスクモデルを使用した.
- 食品頻度アンケートによるアルコール消費の評価と,国家保健レジスタリによるAAA発生率.
- AAAの発生を特定するために,14年間80,000人以上の参加者を追跡しました.
主要な成果:
- 適度なアルコール摂取でAAAの危険性が低下することが観察されました:男性では週10杯 (HR 0.80),女性では週5杯 (HR 0.57).
- 男性におけるビールの消費と女性におけるワインの消費は,AAAリスクと逆相関を示した.
- アルコール摂取とAAAリスクとの間に有意な関連性は見つかりませんでした.
結論:
- ビールとワインの適度な摂取は,腹動脈動脈瘤のリスクの低下と関連しています.
- AAAリスクに対するより高いアルコール消費量の影響は,未定のままです.
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