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Updated: Apr 27, 2026

CRISPR-Cas9-based Genome Engineering to Generate Jurkat Reporter Models for HIV-1 Infection with Selected Proviral Integration Sites
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HIVの潜伏期. 特定のHIV統合部位は,感染した細胞のクローン拡張と持続と関連しています

F Maldarelli1, X Wu2, L Su2

  • 1HIV Drug Resistance Program, National Cancer Institute, Frederick, MD 21702, USA.

Science (New York, N.Y.)
|June 28, 2014
PubMed
まとめ

ヒト免疫不全ウイルス (HIV) のDNAは宿主ゲノムに統合され,治療を受けても感染した細胞に持続します. これらの統合部位は,HIVに感染した細胞の拡大と長期的な生存を促し,治療を妨げています.

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