静脈血栓塞栓症の30年死亡率:集団ベースのコホート研究
Kirstine Kobberøe Søgaard1, Morten Schmidt2, Lars Pedersen2
1From the Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark. kks@clin.au.dk.
Circulation
|June 28, 2014
まとめ
静脈血栓塞栓症 (VTE) の患者は,特に診断後1年以内に,より高い長期的な死亡リスクに直面します. このリスクは30年間持続し,VTEは死亡の重要な原因であるが,肺栓塞では30日間の死亡率が改善している.
科学分野:
- 心血管医学は,心臓血管医学である.
- エピデミオロジー エピデミオロジー
- 公衆衛生は公衆衛生である.
背景:
- 静脈血栓塞栓症 (VTE) の後の長期死亡に関するデータは限られている.
- 深静脈血栓症 (DVT) と肺栓塞 (PE) を含むVTEは,健康に重大な負担を及ぼす.
研究 の 目的:
- 30年間,初めて発症したVTEに関連した長期的な死亡リスクを調査する.
- VTE患者における死亡率を,一致した一般集団のコホートと比較する.
主な方法:
- デンマーク (1980-2011) で実施された全国的な,人口ベースのコホート研究.
- 第一次VTE患者128,223人と,マッチングした対照群640,760人を含む.
- 死亡率比率 (MRRs) を決定するために,デンマークの医療データベースとコックス回帰分析を使用しました.
主要な成果:
- VTE患者は,特に診断後30日以内に,および診断後1年以内に,対照群よりも著しく高い死亡リスクを示しました.
- 30年間の全MRRは,DVTでは1.55で,PEでは2.77でした.
- 30日間のDVT死亡率は安定したままであったが,PE死亡率は30年以上にわたって著しく改善した.
結論:
- VTE患者は,30年間の追跡期間中,高い死亡リスクに直面します.
- VTEは,特に診断後の最初の1年で,死亡率に大きく寄与します.
- PEの30日間の死亡率の改善は,ケアにおける進歩を示唆しますが,DVTの死亡率は依然として懸念事項です.
キーワード:
エピデミオロジー エピデミオロジー死亡率 死亡率 死亡率予後予測 予後予測血栓塞栓症 (Thromboembolism) とは,血栓塞栓症 (Thromboembolism) とは,血栓塞栓症 (Thromboembolism) とは,血栓塞栓症 (Thromboembolism) とは,血栓塞栓症 (Thromboembolism) とは,血栓塞栓症 (Thromboembolism) とは,血栓塞栓症 (Thromboembolism) とは,血栓塞栓症 (Thromboembolism) とは,血栓塞栓症 (Thromboembolism) とは,血栓塞栓症 (Thromboembolism) とは,血栓塞栓症 (Thromboembolism) とは,血栓塞栓症 (Thromboembolism) とは,血栓塞栓症 (Thromboembolism) とは,関連する概念動画
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