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Spatiotemporal Control of Protein Activity through Optogenetic Allosteric Regulation
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分子運動学. 分子運動学. SOSによるRas活性化:変化した波動動力学によるアロステリック調節

Lars Iversen1, Hsiung-Lin Tu1, Wan-Chen Lin1

  • 1Howard Hughes Medical Institute, Department of Chemistry, University of California, Berkeley, Berkeley, CA 94720, USA.

Science (New York, N.Y.)
|July 5, 2014
PubMed
まとめ

シングル・ソン・オブ・セブンレス (SOS) 分子は活性状態の間で変動し,H-Ras信号伝導調節のための新しいモデルを明らかにします. ラス・グアノシン・トリホスファート (GTP) はこれらの動態を調節し,酵素活性に影響を与えます.

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