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Updated: Apr 27, 2026

Author Spotlight: Developing Acetyl-Click Assay for HAT1 Inhibitor Screening
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核のピルバ酸脱水素酶複合体は,アセチル-CoAとヒストンのアセチル化生成に重要である

Gopinath Sutendra1, Adam Kinnaird1, Peter Dromparis1

  • 1Department of Medicine, University of Alberta, Edmonton, AB T6G 2B7, Canada.

Cell
|July 5, 2014
PubMed
まとめ

mitochondrial pyruvate dehydrogenase complex (PDC) は核に移動し,ヒストンのアセチル化のためのアセチル-CoAを生成し,細胞サイクル進行を調節する. この核のPDCは,表遺伝的調節を促進する.

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