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Updated: Jan 10, 2026

Nephrotic Syndrome I : Introduction
01:24

Nephrotic Syndrome I : Introduction

Published on: June 19, 2025

476

マクロファージにおけるERK5の活性化はエフェロシトーシスを促進し,動脈硬化症を抑制する

Kyung-Sun Heo1, Hannah J Cushman2, Masashi Akaike2

  • 1From the Aab Cardiovascular Research Institute and Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY (K.H., H.J.C., C.W., K.F., J.A.); Department of Medical Education, Institute of Health Biosciences, University of Tokushima Graduate School, Kuramoto-cho, Tokushima, Japan (M.A.); Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom (X.W.); and Biostatistics and Computational Biology, University of Rochester School of Medicine and Dentistry, Rochester, NY (X.Q.). Kyung-Sun_Heo@urmc.rochester.edu Jun-ichi_Abe@urmc.rochester.edu.

Circulation
|July 9, 2014
PubMed
まとめ

細胞外信号調節キナーゼ5 (ERK5) は,マクロファージによる死細胞の除去プロセスであるエフェロサイトーシスを強化します. ERK5を抑制することは,動脈硬化やその他の心血管疾患の治療のための新しい戦略を提供することができる.

キーワード:
動脈硬化症 (動脈動脈硬化症) についてシグナルトランスデュークション信号.

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