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Updated: Jul 19, 2026

Biochemical Reconstitution of Steroid Receptor•Hsp90 Protein Complexes and Reactivation of Ligand Binding
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最初の亜鉛指の足首にある2つのアミノ酸は,グルココルチコイド受容体によるDNA応答要素の活性化を規定する

M Danielsen1, L Hinck, G M Ringold

  • 1Department of Pharmacology, Stanford University School of Medicine, California 94305.

Cell
|June 30, 1989
PubMed
まとめ

ステロイド受容体の特定のアミノ酸は,標的遺伝子の活性化を決定する. 最初の亜鉛指のわずかな変化により,受容体は異なるDNA応答要素に結合し,遺伝子調節の重要なメカニズムを明らかにします.

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