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分野を超えた研究への資金提供. 10年後のNIHロードマップ/共同基金について

Francis S Collins1, Elizabeth L Wilder2, Elias Zerhouni2

  • 1National Institutes of Health, Bethesda, MD 20892, USA. francis.collins@nih.gov.

Science (New York, N.Y.)
|July 19, 2014
PubMed
まとめ

No abstract available in PubMed .

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Preclinical development consists of a series of tests that ensure the safety and efficacy of a new therapeutic compound before it is tested in humans. There are four main phases to this process. First, safety pharmacology tests are conducted to ensure the drug does not produce any acutely harmful effects. These tests examine parameters such as bronchoconstriction, cardiac dysrhythmias, blood pressure changes, and ataxia. Next, preliminary toxicological testing is performed to determine the...
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