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アラルミンIL-33は,腸内のT細胞機能を調節する機能を促進します

Chris Schiering1, Thomas Krausgruber1, Agnieszka Chomka1

  • 1Translational Gastroenterology Unit, Nuffield Department of Clinical Medicine, Experimental Medicine Division, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DU, UK.

Nature
|July 22, 2014
PubMed
まとめ

インターリューキン-33 (IL-33) は,腸内の調節性T細胞 (Treg細胞) の機能と生存を高め,抗炎症反応を促進します. しかし,IL-23は,この保護的なIL-33シグナリングを阻害し,慢性腸内炎症に影響を与える可能性があります.

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