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Updated: Apr 26, 2026

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mTORC1によるタンパク質合成と分解の調整された調節

Yinan Zhang1, Justin Nicholatos1, John R Dreier2

  • 1Department of Genetics and Complex Diseases, Harvard School of Public Health, Boston, Massachusetts 02115, USA.

Nature
|July 22, 2014
PubMed
まとめ

ラパミシン複合体1 (mTORC1) のメカニスティックターゲットは,タンパク質の合成と分解を強化する. 活性化されたmTORC1は,核因子エリソイド由来2関連因子1 (NRF1) を通してプロテアソームの容量を増大させ,タンパク質生産のためのアミノ酸の可用性を高めます.

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