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Updated: Apr 26, 2026

Author Spotlight: Identifying Compensatory Pathways in Malaria Parasites Containing Hypomorphic Allele of Essential Protein Kinases
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Author Spotlight: Identifying Compensatory Pathways in Malaria Parasites Containing Hypomorphic Allele of Essential Protein Kinases

Published on: November 22, 2024

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PTEXは,マラリア寄生虫のタンパク質輸出に不可欠な繋がりです

Brendan Elsworth1, Kathryn Matthews2, Catherine Q Nie3

  • 11] Macfarlane Burnet Institute for Medical Research and Public Health, Melbourne, 3004, Australia [2] Monash University, Clayton, Victoria, 3800, Australia [3].

Nature
|July 22, 2014
PubMed
まとめ

輸出されたタンパク質 (PTEX) のプラズモディウムトランスロコン装置は,すべてのマラリア寄生虫タンパク質の輸出に不可欠です. PTEXを妨害すると,寄生虫の成長と毒性の要因の輸出がひどく損なわれ,重要な薬物標的として特定されます.

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