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Updated: Apr 26, 2026

Preparation and Delivery of Protein Microcrystals in Lipidic Cubic Phase for Serial Femtosecond Crystallography
09:09

Preparation and Delivery of Protein Microcrystals in Lipidic Cubic Phase for Serial Femtosecond Crystallography

Published on: September 20, 2016

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ヒトのGPR40受容体の高解像度構造は,アロステリックアゴニストTAK-87575と結合する

Ankita Srivastava1, Jason Yano1, Yoshihiko Hirozane2

  • 11] Department of Structural Biology and Core Sciences &Technology, Takeda California, 10410 Science Center Drive, San Diego, California 92121, USA [2].

Nature
|July 22, 2014
PubMed
まとめ

TAK-875に結合するヒトGPR40受容体の結晶構造は,そのユニークな結合モードを明らかにし,2型糖尿病治療の洞察を提供している. この構造は,TAK-875の理解を助けます.

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