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Updated: Apr 26, 2026

Transmembrane Domain Oligomerization Propensity determined by ToxR Assay
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Published on: May 26, 2011

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超膜ヘリックス6の位置は,受容体Gタンパク質結合特異性を決定する

Alexander S Rose1, Matthias Elgeti, Ulrich Zachariae

  • 1Institut für Medizinische Physik und Biophysik, ‡AG ProteiInformatics, and #AG Protein X-ray Crystallography, Charité-Universitätsmedizin Berlin , Charitéplatz 1, 10117 Berlin, Germany.

Journal of the American Chemical Society
|July 22, 2014
PubMed
まとめ

Gタンパク質結合受容体 (GPCR) は,GiまたはGタンパク質に結合するために異なる形状を使用し,信号特異性に影響を与えます. この研究は,受容体の構造がGタンパク質結合の選択性をどのように決定するかを明らかにしています.

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