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Updated: Apr 26, 2026

Selection of Aptamers for Amyloid β-Protein, the Causative Agent of Alzheimer's Disease
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Selection of Aptamers for Amyloid β-Protein, the Causative Agent of Alzheimer's Disease

Published on: May 13, 2010

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チラルの金属ヘリカル複合体は,アルツハイマー病の治療のためにアミロイドβをエナンチオセレクティブに標的とする

Meng Li1, Suzanne E Howson, Kai Dong

  • 1Laboratory of Chemical Biology, Division of Biological Inorganic Chemistry, State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences , Changchun, Jilin 130022, China.

Journal of the American Chemical Society
|July 26, 2014
PubMed
まとめ

2つの新しいキラル金属複合体は,アミロイドベータの結合をエナンチオセレクティブに阻害し,アルツハイマー病 (AD) 治療のための新しい治療戦略を提供します. これらの複合体は血脳障壁を通過し,抗酸化物質の性質を持っています.

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