臨床試験は費用対効果の高い投資ですか?
1Department of Health Administration, University of Toronto, Ontario, Canada.
JAMA
|October 6, 1989
まとめ
臨床試験は,高価なものであっても,強力な経済的価値を提供します. この研究は,ランダム化試験への投資が費用対効果が高く,人口の健康に重大な利益をもたらすことを示しています.
科学分野:
- 健康経済学 医療経済学
- 臨床研究方法論 臨床研究方法論
- バイオメディカル投資分析
背景:
- 臨床研究の経済的可行性を評価することは,資金配分において極めて重要です.
- 以前の評価は,試験そのものよりも介入に焦点を当てたことが多かった.
- 臨床試験の投資収益性を理解することは,将来の研究優先事項を明確にします.
研究 の 目的:
- ランダム化臨床試験の実施の経済的魅力を評価する.
- 選択されたランダム化試験の費用対効果を定量化する.
- 生物医学研究資金に関する政策立案者向けにデータを提供すること.
主な方法:
- 7つの選択されたランダム化試験を評価するために,費用対効果モデルが開発されました.
- モデルには,試験の実施コストと健康状態の利益の予測が組み込まれました.
- 漸進的費用対効果比 (ICER) は,節約した寿命年当たりで計算された.
主要な成果:
- 研究された試験のICERは,生涯に1年節約する2~3ドル (アスピリンが不安定な心房痛に) から,生涯に1年節約する399~685ドル (冠動脈外科研究) まででした.
- これらの費用対効果の比率は,効果が証明された介入の比率よりも著しく優れていた.
- 結果は,評価された臨床試験が健全な経済的投資であることを示している.
結論:
- 論争の的で高価な臨床試験を含む選択された臨床試験は,経済的に魅力的な投資です.
- 臨床研究の費用対効果は,人口の健康を改善する価値を支持します.
- 生物医学研究,特に適切に設計された試験のための資金調達が正当化されている証拠が示唆されています.
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