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Updated: Apr 26, 2026

Detection of Modified Forms of Cytosine Using Sensitive Immunohistochemistry
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RNAにおける5-hydroxymethylcytosineのテト媒介による形成

Lijuan Fu1, Candace R Guerrero, Na Zhong

  • 1Environmental Toxicology Graduate Program and ‡Department of Chemistry, University of California , Riverside, California 92521, United States.

Journal of the American Chemical Society
|July 30, 2014
PubMed
まとめ

10−11の転位 (Tet) 酵素は,エピジェネティック調節のためにDNA内の5メチルサイトシンを酸化する. 研究者らは,テト酵素がRNAで5-hydroxymethylcytidine (5-hmrC) も生成することを発見し,RNA生物学における新たな役割を示唆した.

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