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マノペプチミシンアグリコネの総合合成とステレオ化学の修正

Shinichiro Fuse1, Hirotsugu Koinuma, Atsushi Kimbara

  • 1Department of Applied Chemistry, Tokyo Institute of Technology , Meguro-ku, Tokyo 152-8552, Japan.

Journal of the American Chemical Society
|August 1, 2014
PubMed
まとめ

研究者は,生物活性非リボソームペプチドの簡潔な合成を開発し,マンノペプチミシンアグリコネの最初の完全合成を可能にしました. これにより,抗薬剤耐性細菌に対する抗生物質の開発が進められます.

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