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Updated: Apr 26, 2026

Biophysical Assays to Probe the Mechanical Properties of the Interphase Cell Nucleus: Substrate Strain Application and Microneedle Manipulation
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Biophysical Assays to Probe the Mechanical Properties of the Interphase Cell Nucleus: Substrate Strain Application and Microneedle Manipulation

Published on: September 14, 2011

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ATRは,機械的なストレスの反応として核封筒のチェックポイントを媒介します

Amit Kumar1, Michele Mazzanti2, Martin Mistrik3

  • 1Fondazione Istituto FIRC di Oncologia Molecolare (IFOM), Via Adamello 16, 20139 Milan, Italy.

Cell
|August 2, 2014
PubMed
まとめ

ATRタンパク質は,核包膜の機械的ストレスに反応し,染色体の完全性を維持するのに役立ちます. この機械的反応は,物理的なストレスの下で細胞の生存に不可欠です.

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