男性における無症状のクラミジアおよびゴノコック感染症の尿白血球エステラーゼスクリーニング検査
M A Shafer1, J Schachter, A B Moscicki
1Department of Pediatrics, University of California, San Francisco 94143.
JAMA
|November 10, 1989
まとめ
尿白血球エステラーゼ検査は,無症状の青少年男性をクラミジア性尿路炎およびゴノコック性尿路炎に効果的にスクリーニングします. この非侵襲的な方法は,それ以外では検出されない感染症を特定し,公衆衛生にとって費用対効果が高くなります.
科学分野:
- 泌尿器科 泌尿器科とは
- 感染症 感染症は感染症です.
- 青少年の健康について
背景:
- クラミジア・トラホマティスおよびネイスリア・ゴンノレアによって引き起こされる尿路炎は,性的に活動的な青少年において一般的です.
- 無症状の感染症は,潜在的な合併症とさらなる感染による公衆衛生上の大きな課題となっています.
- 効果的なスクリーニング方法は,この集団の早期発見と管理に不可欠です.
研究 の 目的:
- 尿白血球エステラゼ (ULE) テストの診断精度を評価するために.
- 培養で検証されたクラミジア性尿道炎およびゴノコック性尿道炎を予測するULEテストの能力を決定する.
- 無症状の青少年男性のスクリーニングツールとしてULEテストを評価する.
主な方法:
- 948人の性的に活発な青少年男性のコホートは,ULEスクリーニングのために最初の捕獲の尿サンプルを提供しました.
- 435人の参加者のサブセットは,クラミジア・トラコマティスとネイスリア・ゴノレアeの尿道培養を受けた.
- ULEテストの感度,特異性,予測値を計算した.
主要な成果:
- ULEテストは,すべての参加者の8%で,培養を受ける者の15%で陽性でした.
- 培養で確認された感染は,9パーセントのクラミジア・トラホマティスと3パーセントのネイセリア・ゴノレアでした.
- ULEテストは72%の感度,93%の特異性,58%の陽性予測値,96%の陰性予測値を示した.
結論:
- 尿白血球エステラーゼ検査は,無症状の青少年男性における尿路炎の価値ある非侵襲的なスクリーニングツールです.
- この費用対効果の高い方法により,培養で確認された多数のクラミジアおよびゴノコック感染症を特定できます.
- ULE検査の実施は,早期発見率を向上させ,性感染症の重荷を若者に軽減することができます.
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