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Sequence-specific Labeling of Nucleic Acids and Proteins with Methyltransferases and Cofactor Analogues
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根幹S-アデノシルメチオニン酵素HydGによって触媒化された可逆のH原子抽象

Benjamin R Duffus1, Shourjo Ghose, John W Peters

  • 1Department of Chemistry and Biochemistry, Montana State University , Bozeman, Montana 59717, United States.

Journal of the American Chemical Society
|August 8, 2014
PubMed
まとめ

この研究は[FeFe]-ヒドロゲンアース生物合成における水素原子抽象を調査しています. 発見は,HydG触媒反応における5'-デオキシアデノシル基の可逆的なメカニズムを明らかにし,これは酵素活性部位形成に不可欠である.

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