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アゴニストと結合したイオノトロプ的グルタミン酸受容体の構造

Maria V Yelshanskaya1, Minfen Li1, Alexander I Sobolevsky2

  • 1Department of Biochemistry and Molecular Biophysics, Columbia University, 650 West 168th Street, New York, NY 10032, USA.

Science (New York, N.Y.)
|August 9, 2014
PubMed
まとめ

研究者らは,ネズミのGluA2受容体が部分的アゴニストと結合する構造を明らかにした. これは,閉じた状態の構造と比較して,イオノトロプ性グルタミン酸受容体 (iGluR) のゲーティングメカニズムに不可欠な構成変化を照らしています.

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