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Updated: Apr 26, 2026

High-throughput Quantitative Real-time RT-PCR Assay for Determining Expression Profiles of Types I and III Interferon Subtypes
10:00

High-throughput Quantitative Real-time RT-PCR Assay for Determining Expression Profiles of Types I and III Interferon Subtypes

Published on: March 24, 2015

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炎症. 炎症. 炎症. 炎症. 炎症. 炎症. 炎症. 炎症. 25-ヒドロキシコレステロールは,I型インターフェロンより下流で発生するインターレウキン1誘発の炎症を抑制する

Andrea Reboldi1, Eric V Dang1, Jeffrey G McDonald2

  • 1Howard Hughes Medical Institute, Department of Microbiology and Immunology, University of California, San Francisco, CA 94143, USA.

Science (New York, N.Y.)
|August 9, 2014
PubMed
まとめ

I型インターフェロン (IFN) 信号は通常,炎症を抑制します. 新しい研究によると,オキシステロール25-ヒドロキシコレステロール (25-HC) がこの鍵であり,それが不足すると,IL-1のような炎症性サイトカインの過剰生産が起こります.

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