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Updated: Apr 25, 2026

Visualization of Inflammatory Caspases Induced Proximity in Human Monocyte-Derived Macrophages
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炎症性カスパスは,細胞内LPSの先天的な免疫受容体である

Jianjin Shi1, Yue Zhao2, Yupeng Wang3

  • 11] Peking University-Tsinghua University-National Institute of Biological Sciences Joint Graduate Program, National Institute of Biological Sciences, Beijing 102206, China [2] National Institute of Biological Sciences, Beijing 102206, China [3].

Nature
|August 15, 2014
PubMed
まとめ

人間のカスパゼ4とカスパゼ5とマウスカスパゼ11は,直接リポポリサッカリド (LPS) に結合し,細胞死経路を誘発する. この発見は,免疫パターン認識とカスパース活性化のための新しいメカニズムを明らかにします.

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