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Updated: May 7, 2026

Improved Protocol for Chromatin Immunoprecipitation from Mouse Skeletal Muscle
09:30

Improved Protocol for Chromatin Immunoprecipitation from Mouse Skeletal Muscle

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ヒトの転写因子Sp1のグルタミンに富んだドメインによるシナギスティック活性化

A J Courey1, D A Holtzman, S P Jackson

  • 1Howard Hughes Medical Institute, Department of Molecular and Cell Biology, University of California, Berkeley 94720.

Cell
|December 1, 1989
PubMed
まとめ

Sp1 (特異性タンパク質1) を含むタンパク質とタンパク質の相互作用は,転写を強化する. Sp1モノマーが相互作用し,遠隔のDNA部位からでも,またはDNA結合欠陥のある変異体からでも,シネギスティックな活性化を可能にします.

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