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Updated: Apr 25, 2026

Monitoring Hippo Signaling Pathway Activity Using a Luciferase-based Large Tumor Suppressor LATS Biosensor
07:16

Monitoring Hippo Signaling Pathway Activity Using a Luciferase-based Large Tumor Suppressor LATS Biosensor

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ヒッポの経路は,プロイディのチェックポイントへの鍵です

Bin Zhao1, Kun-Liang Guan2

  • 1Life Sciences Institute and Innovation Center for Cell Biology, Zhejiang University, Hangzhou, Zhejiang 310058, China.

Cell
|August 16, 2014
PubMed
まとめ

テトラプロイド細胞は,しばしば細胞サイクル停止またはアポトーシスによって除去され,生き残れば癌を引き起こす可能性があります. 余分なセンターソームはLATS2キナーゼを活性化させ,これはテトラプロイド細胞の細胞分裂を停止する重要なメカニズムである.

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