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Updated: Apr 25, 2026

In Vitro Differentiation of Human CD4+FOXP3+ Induced Regulatory T Cells (iTregs) from Naïve CD4+ T Cells Using a TGF-β-containing Protocol
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In Vitro Differentiation of Human CD4+FOXP3+ Induced Regulatory T Cells (iTregs) from Naïve CD4+ T Cells Using a TGF-β-containing Protocol

Published on: December 30, 2016

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調節性T細胞の同一性を保護するFoxp3シス要素の機能

Xudong Li1, Yuqiong Liang1, Mathias LeBlanc1

  • 1Nomis Foundation Laboratories for Immunobiology and Microbial Pathogenesis, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA.

Cell
|August 16, 2014
PubMed
まとめ

特定のDNA要素である保存非コーディング配列2 (CNS2) は,T (Treg) 細胞の同一性を保護する. この表遺伝的メカニズムは,免疫ホメオスタシスを維持し,環境のシグナルを感知することで,自己免疫疾患を予防します.

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