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Updated: Jul 18, 2026

Inducible and Reversible Dominant-negative (DN) Protein Inhibition
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Published on: January 7, 2019

Jun-Bは,その生物学的性質によって,c-Junの負の調節体であり,c-Junと異なる

R Chiu1, P Angel, M Karin

  • 1Department of Pharmacology, School of Medicine, University of California, San Diego, La Jolla 92093.

Cell
|December 22, 1989
PubMed
まとめ

ジュン族のタンパク質であるc-ジュンとジュン-Bは,異なる遺伝子活性化能力を有する. c-Junは単一のTPA応答要素 (TRE) プロモーターを効率的に活性化しますが,Jun-Bは活性化のために複数のTREと協力的な相互作用を必要とし,Junタンパク質の調節作用を拡大します.

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