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Updated: Apr 25, 2026

Combining Chemical Cross-linking and Mass Spectrometry of Intact Protein Complexes to Study the Architecture of Multi-subunit Protein Assemblies
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Combining Chemical Cross-linking and Mass Spectrometry of Intact Protein Complexes to Study the Architecture of Multi-subunit Protein Assemblies

Published on: November 28, 2017

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紫外線光解離質量スペクトロメトリを用いたネイティブタンパク質複合体の特徴づけ

John P O'Brien1, Wenzong Li, Yan Zhang

  • 1Department of Chemistry, ‡Department of Molecular Biosciences, and §Institute for Cellular and Molecular Biology, The University of Texas at Austin , 105 East 24th Street Stop A5300, Austin, Texas 78712, United States.

Journal of the American Chemical Society
|August 23, 2014
PubMed
まとめ

紫外線光解離 (UVPD) 質量スペクトロメトリは,複合体のための包括的なタンパク質配列データを提供します. この方法は,タンパク質構造とリガンド結合部位を詳細に記述する他の方法よりも優れています.

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