人間と室内の環境の間の微生物の相互作用の縦断分析
Simon Lax1, Daniel P Smith2, Jarrad Hampton-Marcell1
1Department of Ecology and Evolution, University of Chicago, 1101 E 57th Street, Chicago, IL 60637, USA. Institute for Genomic and Systems Biology, Argonne National Laboratory, 9700 South Cass Avenue, Argonne, IL 60439, USA.
Science (New York, N.Y.)
|August 30, 2014
まとめ
人間は,家の中の細菌の主要な源であり,室内の微生物群を形作る. 引っ越した後,ある家族が引っ越した.
科学分野:
- マイクロバイオームの研究
- 環境微生物学 環境微生物学
- 人間と微生物の相互作用
背景:
- 人間の環境をコロニー化した細菌は,健康に影響を及ぼします.
- 室内の微生物コミュニティの源泉とダイナミクスを理解することは極めて重要です.
研究 の 目的:
- 家庭内の微生物コミュニティの発生源と伝播を調査する.
- 家族が引っ越すことで,家庭の微生物群にどのような影響があるかを評価するためです.
主な方法:
- 7つの家族とその住居の微生物群を6週間追跡した.
- ネットワーク分析とベイジアン法を使用して,バクテリア源を特定しました.
- 潜在的病原体に対して全ゲノム配列解析を行った.
主要な成果:
- 家庭の微生物群は,主に人間の居住者から派生しました.
- 家族は,独特の家庭の微生物群によって識別できた.
- 人間が主要なバクテリアベクトルとして特定されました.
- 表面の潜在的な病原菌は,乗員の手と関連していた.
- 新しい家にある微生物のコミュニティは,引っ越し後の古い家にある微生物のコミュニティに急速に似ている.
結論:
- 人間に関連したバクテリアは,室内の微生物群を著しく形作る.
- 家庭の微生物群は,その居住者によって大きく決定されます.
- 家族は,移転後,特徴的な微生物群を迅速に回復します.
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