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Updated: Apr 25, 2026

Assessment of Resistance to Tyrosine Kinase Inhibitors by an Interrogation of Signal Transduction Pathways by Antibody Arrays
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分泌されたチロシンキナーゼは,細胞外環境で作用する

Mattia R Bordoli1, Jina Yum2, Susanne B Breitkopf3

  • 1Department of Developmental Biology, Harvard School of Dental Medicine, Boston, MA 02115, USA.

Cell
|August 30, 2014
PubMed
まとめ

研究者らは,新しい分泌タンパク質チロシンキナーゼであるVascular Like Kinase (VLK) を発見した. この発見は,細胞外チロシンリン酸化がイン・ビヴォで広範囲に及んでおり,組織調節におけるチロシンリン酸化の役割も説明できる.

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