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Morphogenesis02:19

Morphogenesis

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Plant morphogenesis—the development of a plant’s form and structure—involves several overlapping developmental processes, including growth and cell differentiation. Precursor cells differentiate into specific cell types, which are organized into the tissues and organ systems that make up the functional plant.
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Gastrulation01:56

Gastrulation

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Gastrulation establishes the three primary tissues of an embryo: the ectoderm, mesoderm, and endoderm. This developmental process relies on a series of intricate cellular movements, which in humans transforms a flat, “bilaminar disc” composed of two cell sheets into a three-tiered structure. In the resulting embryo, the endoderm serves as the bottom layer, and stacked directly above it is the intermediate mesoderm, and then the uppermost ectoderm. Respectively, these tissue strata...
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Neurulation01:30

Neurulation

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Neurulation is the embryological process which forms the precursors of the central nervous system and occurs after gastrulation has established the three primary cell layers of the embryo: ectoderm, mesoderm, and endoderm. In humans, the majority of this system is formed via primary neurulation, in which the central portion of the ectoderm—originally appearing as a flat sheet of cells—folds upwards and inwards, sealing off to form a hollow neural tube. As development proceeds, the...
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Cleavage and Blastulation01:33

Cleavage and Blastulation

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After a large-single-celled zygote is produced via fertilization, the process of cleavage occurs while zygotes travel through the uterine tube. Cleavage is a mitotic cell division that does not result in growth. With each round of successive cell division, daughter cells get increasingly smaller.
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Vascular plants, which account for over 90% of the Earth’s vegetation, all undergo primary growth—which lengthens roots and shoots. Many land plants, notably woody plants, also undergo secondary growth—which thickens roots and shoots.
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The skeletal structure of polymers synthesized via radical polymerization is always branched. For example, the polymerization of ethylene by radical polymerization results in a low-density grade of polyethylene with a heavily branched skeletal structure. Here, the radical site abstracts hydrogen from the growing chain, and the radical site shifts from the end (a primary carbon center) to anywhere within the growing chain (a secondary carbon center). Consequently, the part of the chain from the...
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Analyzing Craniofacial Morphogenesis in Zebrafish Using 4D Confocal Microscopy
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スナップショット: 枝分かれする形質変異

Cheng-Ming Chuong1, Ramray Bhat2, Randall B Widelitz3

  • 1Department of Pathology, University of Southern California, Los Angeles, CA 90033, USA; Center of Wound Repair and Regeneration, Cheng Kung University, Tainan, Taiwan.

Cell
|August 30, 2014
PubMed
まとめ
この要約は機械生成です。

羽毛や乳腺のような外皮の付属体における分岐形態変異は,機能のための表面積を増加させます. この研究は,この重要な発達プロセスを支配する基本的な原則を探求します.

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科学分野:

  • 発達生物学 発達生物学とは
  • モルフォゲネシス (Morphogenesis) モルフォゲネシスとは
  • 細胞生物学 細胞生物学

背景:

  • 羽毛,毛,乳腺,唾液腺,汗腺を含む外皮の付属体は,複雑な分岐構造を示しています.
  • 枝分かれにより,表面積が大幅に増加し,これは分泌や分化などの特殊な機能に不可欠です.

研究 の 目的:

  • 枝分かれ形質変異の基本原理を解明する.
  • 乳腺と羽の発達をモデルシステムとして使用し,これらの原則を例示する.

主な方法:

  • 乳腺と羽根の分岐パターンの比較分析.
  • エピテリアの分岐を駆動する基礎となる分子および細胞機構の調査.

主要な成果:

  • 多様な外皮付属体における枝分かれを調節する保存されたメカニズムを特定する.
  • 枝分かれ形質変異が,分泌と分化のための機能的表面積を最適化する方法の実証.

結論:

  • 枝分かれ形質変異は,外皮付属体の重要な発達戦略である.
  • 乳腺や羽毛などのモデルでこれらの原理を理解することは,より広範な発達生物学への洞察を提供します.