急性 perikarditisのために入院した患者の臨床プロファイルと結果への影響
Ville Kytö1, Jussi Sipilä2, Päivi Rautava2
1From the Heart Center, (V.K.), Clinical Neurosciences, Neurology (J.S.), and Clinical Research Center (P.R.), Turku University Hospital, and PET Center (V.K.), Neurology (J.S.), and Public Health (P.R.), University of Turku, Turku, Finland. ville.kyto@utu.fi.
Circulation
|September 11, 2014
まとめ
急性 perikarditisは男性においてより一般的です. 急性心膜炎の入院死亡率は,年齢や重症共感染とともに増加するが,性別はそうではない.
科学分野:
- 心臓病学 心臓病学
- エピデミオロジー エピデミオロジー
- クリニカル・メディシン 臨床医学
背景:
- 急性心膜炎の臨床的特徴,特に性差および結果の予測要因について,十分に理解されていません.
- 既存の研究は,急性心周炎で入院した患者の人口統計学的および臨床的プロフィールを完全に明らかにしていない.
研究 の 目的:
- 性別による差異に焦点を当てて臨床プロフィールを調査し,急性心膜炎で入院した患者のアウトカムに影響を与える要因を特定する.
- 急性心膜炎入院の発生率と人口分布を決定する.
主な方法:
- 9.5年以上にわたる心血管疾患の入院者のフィンランドの国立レジストリを利用した全国的な遡及研究.
- 分析対象は,16歳以上の急性心膜炎で入院した1361例で,心膜切開後の心筋梗塞や心筋梗塞に関連した心膜炎などの特定のタイプを除いた.
- 統計的方法には,年齢調整された確率比,相対リスク計算,および死亡率予測要因を評価するための多変量分析が含まれていました.
主要な成果:
- 急性 perikarditisは,女性 (35.1%) よりも男性 (64.9%) でより一般的であり,16歳から65歳までの男性ではより高いリスクが観察されました.
- 急性心膜炎入院の標準化発生率は10万人年あたり3.32であり,年齢とともに減少しています.
- 病院での死亡率は1.1%で,年齢や重症共感染 (肺炎または結血病) の存在により有意に増加しているが,性別に関連していない.
結論:
- 男性の性別は,急性 perikarditis のために入院する重要な人口統計的要因です.
- 高齢と重症共感染は,急性心膜炎患者の入院死亡率の増加の重要な予測要因です.
- 性別は,急性心膜炎における入院死亡率の独立した予測因子ではないようです.
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