関連する実験動画

Updated: Apr 24, 2026

DNA Sequence Recognition by DNA Primase Using High-Throughput Primase Profiling
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プライマー・アンニング中のtRNAとレトロウイルスRNAの改造のための構造に基づくメカニズム

Sarah B Miller1, F Zehra Yildiz2, Jennifer A Lo3

  • 11] Department of Molecular and Cellular Biology, Harvard University, Cambridge, Massachusetts 02138, USA [2] Department of Biology, Georgetown University, Washington DC 20057, USA. [3].

Nature
|September 12, 2014
PubMed
まとめ

レトロウイルス核カプシド (NC) タンパク質はRNA構造を改造し,逆転写のためのプライマーアニリングを可能にします. このチャペロンは,本質的な残留物を特に標的にして放出し,RNAとタンパク質の相互作用のための新しいメカニズムを明らかにします.

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