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Updated: Apr 24, 2026

A Method to Assess Fc-mediated Effector Functions Induced by Influenza Hemagglutinin Specific Antibodies
04:47

A Method to Assess Fc-mediated Effector Functions Induced by Influenza Hemagglutinin Specific Antibodies

Published on: February 23, 2018

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広範に中和する抗HIV-1抗体は,体内活動のためのFcエフェクタ機能を必要とします

Stylianos Bournazos1, Florian Klein2, John Pietzsch2

  • 1Laboratory of Molecular Genetics and Immunology, The Rockefeller University, New York, NY 10065, USA.

Cell
|September 13, 2014
PubMed
まとめ

広範な中和性抗体 (bNAbs) は,HIV-1の予防と治療に有望であることが示されています. 彼らのFcドメインは,FcγRの関与を活性化させ,保護を強化することで,in vivoの有効性にとって不可欠です.

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