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Updated: Apr 23, 2026

Tissue Preparation Techniques for Contrast-Enhanced Micro Computed Tomography Imaging of Large Mammalian Cardiac Models with Chronic Disease
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移植された心臓における高圧性心筋症のマルチモダリティーイメージング

Siddique A Abbasi1, Michael K Cheezum1, Nina Ghosh1

  • 1From the Noninvasive Cardiovascular Imaging Section, Cardiovascular Division, Departments of Medicine and Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (S.A.A., M.K.C., N.G., M.F.D.C.); and Division of Cardiovascular Medicine, Center for Advanced Heart Disease, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (G.C.S.).

Circulation
|September 17, 2014
PubMed
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No abstract available in PubMed .

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Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
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