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Updated: Apr 23, 2026

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現代の (+) - ゲルマクリーンAシンタゼからα-ヒュームレンシンタゼの再構築による進化的および機械的洞察

Veronica Gonzalez1, Sabrina Touchet, Daniel J Grundy

  • 1School of Chemistry and ‡Cardiff Catalysis Institute, School of Chemistry, Cardiff University , Main Building, Park Place, Cardiff CF10 3AT, United Kingdom.

Journal of the American Chemical Society
|September 18, 2014
PubMed
まとめ

ゲルマクレンA合成酵素 (GAS) の活性については,活性部位の残基を変化させることで調査した. GASにおけるグリシン402の置換とGDSにおけるグリシン404は,セスクイテルペン合成酵素の進化経路を明らかにした.

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