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Updated: Apr 23, 2026

Author Spotlight: Characterizing Novel Enzymes from Extremophiles and Common Pathogens to Understand DNA Repair and Replication
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FeMo共因子へのリガンド結合:CO結合および活性化された窒素酵素酵素の構造

Thomas Spatzal1, Kathryn A Perez2, Oliver Einsle3

  • 1Howard Hughes Medical Institute and Division of Chemistry and Chemical Engineering, MailCode 114-96, California Institute of Technology, Pasadena, CA 91125, USA. spatzal@caltech.edu dcrees@caltech.edu.

Science (New York, N.Y.)
|September 27, 2014
PubMed
まとめ

炭素一酸化物 (CO) は,鉄-モリブデン共同因子 (FeMo共同因子) に結合することによって,窒素酶を逆転的に抑制する. この構造的研究は,CO結合が重要な,可逆的なコファクター再編成を引き起こし,反応性のある鉄種を発見することを明らかにしています.

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