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Updated: Apr 23, 2026

Reprograming Model of Human Monocyte-derived Macrophages for In-vitro Assays
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モノサイトからマクロファージへの差異化と,訓練された先天性免疫のエピジェネティックプログラミング

Sadia Saeed1, Jessica Quintin2, Hindrik H D Kerstens1

  • 1Department of Molecular Biology, Faculties of Science and Medicine, Radboud Institute for Molecular Life Sciences, Radboud University, 6500 HB Nijmegen, Netherlands.

Science (New York, N.Y.)
|September 27, 2014
PubMed
まとめ

単細胞がマクロファージに分化することは宿主防御の鍵です. この研究は,表遺伝的変化によって駆動される訓練された免疫が,マクロファージの機能と感染に対する感受性をどのように変化させるかを明らかにしています.

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