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Fertility Preservation in Patients with Severe Ovarian Dysfunction
Published on: March 25, 2021
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年齢に関連する生育率低下に対する生育率の保全
Dominic Stoop1, Ana Cobo2, Sherman Silber3
1Centre for Reproductive Medicine, UZ Brussel, Brussels, Belgium.
Lancet (London, England)
|October 7, 2014
まとめ
卵子および卵巣組織の冷凍保存を用いた生育保存は,がん患者および妊娠を遅らせている患者にとって希望をもたらします. 成功した出産は,これらの高度な生殖技術の臨床的有効性を実証しています.
科学分野:
- 生殖医学は,生殖器医学である.
- 腫瘍学 腫瘍学
- クリオバイオロジーは,
背景:
- 癌患者の生育保存は20世紀半ばから研究されている.
- 卵細胞および卵巣組織の冷凍保存は,特に非医学的な用件において,臨床的に成功していることが示されています.
- 治療が遅れたため,冷凍保存卵を使用したがん患者の妊娠は限られていると報告されています.
研究 の 目的:
- 卵子と卵巣組織の冷凍保存の臨床的成功と応用をレビューする.
- がん患者および年齢関連の生育能力低下の両方に対するこれらの技術の可能性を評価する.
- 育児保全戦略の進歩を強調する.
主な方法:
- 卵子および卵巣組織の冷凍保存に関する歴史的および臨床データのレビュー.
- 成功した妊娠と出産の結果を分析する.
- 冷凍保存技術とその適用性の比較.
主要な成果:
- 社会的な理由から冷凍保存された卵子から生まれた健康な子供たちが数多くいる.
- 癌患者の卵巣組織を冷凍保存し,生殖能力を回復させた結果,35人以上の赤ちゃんが生まれました.
- 卵子回収のための卵巣刺激は,がん治療を遅らせることができ,卵巣組織の冷凍保存を有効な代替手段にします.
結論:
- 卵子および卵巣組織の冷凍保存は,有効な生育保存方法です.
- これらの技術は,がん患者にとって有望であり,年齢関連の生育率低下に対処しています.
- 冷凍保存の進歩は,生殖能力を保存するための選択肢を拡大しています.
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