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Updated: Apr 23, 2026

Identification of Mediators of T-cell Receptor Signaling via the Screening of Chemical Inhibitor Libraries
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Identification of Mediators of T-cell Receptor Signaling via the Screening of Chemical Inhibitor Libraries

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T細胞受容体によるコアレセプタースキャニングは,T細胞の耐性に対するメカニズムを提供します

Ondrej Stepanek1, Arvind S Prabhakar2, Celine Osswald1

  • 1Departments of Biomedicine and Nephrology, University Hospital Basel and University of Basel, 4031 Basel, Switzerland.

Cell
|October 7, 2014
PubMed
まとめ

発達中のT細胞は,結合されたCD4/CD8コレセプターとLckキナーゼをスキャンすることによって自己抗原親和性を測定します. この運動校正はT細胞の耐性を決定し,自己免疫を予防します.

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