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Updated: Jul 30, 2026

Coupled Assays for Monitoring Protein Refolding in Saccharomyces cerevisiae
13:52

Coupled Assays for Monitoring Protein Refolding in Saccharomyces cerevisiae

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ミトコンドリアにおけるタンパク質の折り畳みは,hsp60とATPの水解による複雑な形成を必要とします

J Ostermann1, A L Horwich, W Neupert

  • 1Institut für Physiologische Chemie der Universität München, FRG.

Nature
|September 14, 1989
PubMed
まとめ

ミトコンドリアの熱ショックタンパク質60 (hsp60) は,ミトコンドリア内の折りたたみタンパク質を支援します. このプロセスには,hsp60表面のATP媒介反応が関与し,ポリペプチドの放出につながり,hsp60がタンパク質の折り畳みを触媒化することを示唆しています.

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