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Updated: Apr 22, 2026

Generation of Escape Variants of Neutralizing Influenza Virus Monoclonal Antibodies
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余剰変異による広範囲のインフルエンザ中和抗体の急速な発達

Leontios Pappas1, Mathilde Foglierini1, Luca Piccoli1

  • 1Insitute for Research in Biomedicine, Università della Svizzera Italiana, Via Vincenzo Vela 6, 6500 Bellinzona, Switzerland.

Nature
|October 9, 2014
PubMed
まとめ

インフルエンザのヘマグルチニン幹を標的とする広範に中和する抗体は稀です. この研究は,VH1-69アレル多形態主義を含む,重要な遺伝的要素と変異を明らかにし,それらの発達と広範な反応性のために必要である.

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