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Updated: Apr 22, 2026

Prediction and Validation of Gene Regulatory Elements Activated During Retinoic Acid Induced Embryonic Stem Cell Differentiation
09:07

Prediction and Validation of Gene Regulatory Elements Activated During Retinoic Acid Induced Embryonic Stem Cell Differentiation

Published on: June 21, 2016

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エンハンサーの活性化には,メガ転写因子複合体のトランスリクルートが必要である

Zhijie Liu1, Daria Merkurjev2, Feng Yang1

  • 1Howard Hughes Medical Institute, Department of Medicine, School of Medicine, University of California, San Diego, La Jolla, CA 92093, USA.

Cell
|October 11, 2014
PubMed
まとめ

強力な増強剤は,メガトランス増強剤と呼ばれる大きなタンパク質複合体を採用して,細胞特異的な遺伝子活性を駆動します. この発見は,トランスクリプション因子が,細胞の重要なプログラムを調節するために,どのように集まっているかを説明します.

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Author Spotlight: An Integrated Workflow to Study the Promoter-Centric Spatio-Temporal Genome Architecture in Scarce Cell Populations11:36

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Promoter Capture Hi-C: High-resolution, Genome-wide Profiling of Promoter Interactions10:16

Promoter Capture Hi-C: High-resolution, Genome-wide Profiling of Promoter Interactions

Published on: June 28, 2018

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