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関連する概念動画

Nervous Tissue: Myelin01:25

Nervous Tissue: Myelin

11.9K
The myelin sheath is a multilayered lipid and protein covering that insulates the axon of a neuron, enhancing the speed of nerve impulse conduction. Axons without this sheath are referred to as unmyelinated. Two types of neuroglia, Schwann cells in the peripheral nervous system (PNS) and oligodendrocytes in the central nervous system (CNS) are responsible for producing myelin sheaths.
Schwann cells begin to form myelin sheaths around axons during fetal development. They wrap around a small...
11.9K
Direct Motor Pathways01:11

Direct Motor Pathways

4.6K
The direct motor pathways, also known as the pyramidal tracts, are a group of neural pathways that originate in the brain and descend through the spinal cord. They control the voluntary movement of the body. There are two major direct motor pathways: the corticospinal and the corticobulbar tracts.
The corticospinal tract is responsible for the voluntary movement of the limbs and trunk. It originates in the cerebral cortex of the brain and descends through the cerebrum's internal capsule and...
4.6K
Hierarchy of Motor Control01:18

Hierarchy of Motor Control

5.5K
The hierarchy of motor control refers to the different levels of organization and processing involved in controlling movement in the body. These levels range from higher cortical areas involved in planning and decision-making to lower spinal cord reflexes that respond automatically to external stimuli.
5.5K
Brainstem01:19

Brainstem

7.3K
The brainstem, located inferior to the brain and superior to the spinal cord, serves as a bridge between the cerebrum and the spinal cord. It plays a vital role in relaying information and controlling critical life functions. It comprises three primary regions: the midbrain, pons, and medulla oblongata.
The Midbrain
The midbrain is located beneath the diencephalon and connects the cerebrum with the lower parts of the brain. The cerebral peduncles are prominent midbrain structures that house the...
7.3K
Motor Units01:13

Motor Units

14.2K
The motor unit is a fundamental component of the neuromuscular system and plays a crucial role in coordinating muscle contractions. It consists of a somatic motor neuron, which connects and controls multiple skeletal muscle fibers, forming a single functional segment. The axon of the motor neuron branches out and establishes synaptic connections known as neuromuscular junctions with individual muscle fibers within the motor unit.
Motor units come in different sizes, with smaller units...
14.2K
Spinal Cord: Cross-sectional Anatomy01:16

Spinal Cord: Cross-sectional Anatomy

5.5K
The cross-sectional anatomy of the spinal cord offers a detailed view of its complex structure and function within the central nervous system. At the core of the spinal cord lies the gray matter, characterized by its butterfly or "H"-shaped appearance in cross-section. This central region is enveloped by white matter, with the overall structure divided into symmetrical halves by the dorsal median sulcus and the ventral median fissure.
Gray Matter and its Components
Central to the gray matter is...
5.5K

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関連する実験動画

Updated: Apr 22, 2026

Study Motor Skill Learning by Single-pellet Reaching Tasks in Mice
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Study Motor Skill Learning by Single-pellet Reaching Tasks in Mice

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運動スキルの学習には,活発な中央ミエリン化が必要です.

Ian A McKenzie1, David Ohayon1, Huiliang Li1

  • 1The Wolfson Institute for Biomedical Research, University College London, Gower Street, London WC1E 6BT, UK.

Science (New York, N.Y.)
|October 18, 2014
PubMed
まとめ
この要約は機械生成です。

新しいオリゴデンドロサイト (OL) とミエリンは,運動スキルの学習に不可欠です. 成人マウスの新しいOL生産をブロックすると,複雑な運動作業をマスターする能力が低下し,脳の可塑性におけるこれらの細胞の役割を強調しました.

さらに関連する動画

Author Spotlight: Unveiling Neural Mechanisms Through Automated Evaluation of Motor Learning and Myelin Plasticity Studies Using the Erasmus Ladder
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Author Spotlight: Unveiling Neural Mechanisms Through Automated Evaluation of Motor Learning and Myelin Plasticity Studies Using the Erasmus Ladder

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Acquisition of a High-precision Skilled Forelimb Reaching Task in Rats
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Acquisition of a High-precision Skilled Forelimb Reaching Task in Rats

Published on: June 22, 2015

9.9K

関連する実験動画

Last Updated: Apr 22, 2026

Study Motor Skill Learning by Single-pellet Reaching Tasks in Mice
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Published on: March 4, 2014

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Author Spotlight: Unveiling Neural Mechanisms Through Automated Evaluation of Motor Learning and Myelin Plasticity Studies Using the Erasmus Ladder
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科学分野:

  • 神経科学は神経科学である.
  • 細胞生物学 細胞生物学
  • 神経可塑性とは 神経可塑性のことです.

背景:

  • オリゴデンドロサイト (OLs) は成人の脳で絶えず形成され,ミエリンを産生します.
  • ホワイトマターの構造は,運動スキルの獲得とともに変化し,OLsの役割を示唆しています.

研究 の 目的:

  • 新しく形成されたOLsとそのミエリンが運動学習における機能を調査する.
  • 新しい運動スキルを習得するために大人のOL生産が必要かどうかを判断する.

主な方法:

  • 新しい運動技能 (複雑な車輪走行) を学習するマウスを研究した.
  • OL前駆体における遺伝子操作されたミエリン調節因子は,新しいOLの産生を阻害する.
  • 遺伝子組み換えマウスと対照マウスの運動学習能力を評価した.

主要な成果:

  • 新しいOLの生産は,複雑なホイールタスクを学習するマウスで加速されました.
  • 新しいOL世代をブロックすると,マウスが複雑なホイールをマスターするのを防ぐことができました.
  • 既存のOLとミエリンは,遺伝子操作の影響を受けなかった.

結論:

  • 新しいオリゴデンドロサイトとミエリンの生成は,運動スキルの学習に不可欠です.
  • OLsの成人神経生成は,脳の可塑性および運動適応において重要な役割を果たします.