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Updated: Apr 21, 2026

Nanomanipulation of Single RNA Molecules by Optical Tweezers
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Published on: August 20, 2014

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生物学的に機能するヒドロキシコバラミンリボスイッチの単分子構成動態

Erik D Holmstrom1, Jacob T Polaski, Robert T Batey

  • 1JILA, University of Colorado and National Institute of Standards and Technology, and ‡Department of Chemistry and Biochemistry, University of Colorado , Boulder, Colorado 80309-0440, United States.

Journal of the American Chemical Society
|October 18, 2014
PubMed
まとめ

リガンド結合は,リボスイッチにおけるキスループの相互作用を安定させ,トランスレーションの開始を防ぐ. 単分子FRETで観察されたこの分子スイッチメカニズムは,細菌の遺伝子発現を調節する.

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