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Updated: Apr 21, 2026

Somatic Genome-Engineered Mouse Models Using In Vivo Microinjection and Electroporation
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ソマティックゲノム編集によるがんにおける協力的な遺伝事象の急速なモデリング

Francisco J Sánchez-Rivera1, Thales Papagiannakopoulos2, Rodrigo Romero1

  • 11] David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA [2] Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA.

Nature
|October 23, 2014
PubMed
まとめ

研究者は新しいCRISPR/Cas9方法を開発し,マウスモデルで癌を引き起こす遺伝子を素早くテストしました. このアプローチは,腫瘍の発症を誘発する重要な突然変異を特定し,がん遺伝子の発見を進めるのに役立ちます.

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