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In Vitro Ubiquitination and Deubiquitination Assays of Nucleosomal Histones
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ポリユビキチル化は,DNA複製の終点におけるレプリソームの分解を誘発する

Sara Priego Moreno1, Rachael Bailey1, Nicholas Campion1

  • 1School of Cancer Sciences, University of Birmingham, Vincent Drive, Birmingham B15 2TT, UK.

Science (New York, N.Y.)
|October 25, 2014
PubMed
まとめ

Mcm7のポリユビキチル化は,DNA複製の終了時にレプリソームの分解を誘発する. このプロセスは,p97/VCP/Cdc48タンパク質リモデレータを伴うもので,真核生物のゲノムを正確に複製することを保証します.

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