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ミトコンドリアの鉄硫黄クラスター組立機械における [4Fe-4S] クラスターの形成

Diego Brancaccio1, Angelo Gallo, Maciej Mikolajczyk

  • 1Department of Pharmacy, University of Naples "Federico II" , Via D. Montesano 49, 80131 Napoli, Italy.

Journal of the American Chemical Society
|October 28, 2014
PubMed
まとめ

人間のISCA1およびISCA2タンパク質は,鉄と硫黄のクラスタを組み立てる複合体を形成します. この異体複合体は,ヒトのGRX5から [2Fe-2S] クラスターを受け取り,ミトコンドリア機能のための [4Fe-4S] クラスターを生み出します.

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